2005-05-27: Upcoming HapMap data release.

After closely examining the genotypes from phase I, some SNPs have been determined to have issues which makes their genotypes be of low quality or incorrect. A new release is being prepared, which corrects for these issues. It is anticipated that this release will come next week. In the interim, a description of the issues, and lists of affected SNPs can be found here.

2005-03-01: HapMap public release #16.
ATTN: This the so-called Phase I data freeze which marks a major milestone of the project: a genotyped common SNP every 5Kb in all populations under study. Data available for bulk download and graphical browsing. Summary of genotyped SNPs:

2005-02-18: HapMap public release #15.
Additional information about the samples/individuals for the Han Chinese, Japanese and Yoruba population is available here. Please note, the genotypes are available for bulk download only. A release update will follow as early as next week, providing the full GBrowse graphical component. Summary of genotyped SNPs:

2005-02-18: Scheduled Network Outage -Japanese Mirror Site
Due to schedule network maintenance at Japan Science and Technology Agency, HapMap (and the related production sites) will be unavailable between 6.00PM(JST) on Feb 18th until approximately 11.00AM (JST) on Feb 21st. We apologize for the disruption. However, the main site will be available as usual.

2004-12-10: It is no longer necessary to sign a clickwrap agreement in order to access HapMap genotype data.
Users are asked to respect the terms of the data usage guidelines, which ensures free and unencumbered access to the data. A copy of the old agreement is available for reference.

2004-12-10:Conference Announcement: Genomic Studies and the HapMap, University of Oxford, UK: March 15-18, 2005

By March 2005, Phase I of the HapMap (600,000 common SNPs typed in 270 individuals) will be complete and Phase II (an additional 2.25M SNPs in the same samples) will be well underway. But there remain many unresolved questions about how best to utilize this information in genetic research. This conference will be hosted by the Department of Statistics at the University of Oxford and its primary focus will be the use of the HapMap resource in genomic studies: human disease studies, and other population genetic and evolutionary analyses.

"Genomic Studies and the HapMap" will provide an important opportunity for a diverse community of investigators-those involved directly in the International HapMap Project, those in the broader analysis community, and those whose focus is disease studies-to come together to define and discuss a range of issues related to the use of the HapMap resource. It will also provide up-to-date assessments of the progress and results from the project. Invited speakers from outside the HapMap project include Andy Clarke, David Clayton, Mark McCarthy, Jonathan Pritchard, Matthew Stephens, and Simon Tavare. This conference follows a successful meeting held in the spring of 2004, which brought together well over 100 participants interested in methods and analysis related to the International Haplotype Map Project.

We invite participation and registration for this meeting and encourage the submission of abstracts for posters or short presentations.
The deadline for submitting an abstract is January 28, 2005.
The deadline for registration/lodging reservations is February 25, 2005.
Complete instructions for abstract submission and registration, and further details of the conference, can be found at the conference Web site, http:/www.hapmap.org/oxford_conference/default.html

2004-12-10: HapMap public release #14.
Additional information about the samples/individuals for the Han Chinese, Japanese and Yoruba population is available here. The genotypes are available for bulk download. Summary of genotyped SNPs:

2004-11-23: HapMap public release #13 now has data for all the HapMap Populations.
Additional information about the samples/individuals for the Han Chinese, Japanese and Yoruba population is available here. The genotypes are available for bulk dowmload. Summary of genotyped SNPs:

2004-10-12: New Generic Genome Browser Feature
LD, Heterozygosity and SNP coverage tracks are now available for viewing. Three LD properties LOD score, D' and r² visualized. Overview tracks on the browser can now be turned on/off. New representation of the allele frequency information on the Genotype SNP track.

2004-10-12: Protocols used in the Project now available
New Protocols page has information on assay design, genotyping, and data submission processing used in the project.

2004-10-12 : Public data release #12
Genotypes, frequencies and assays for 752,208 SNPs (67,698,720 genotypes) released for bulk download and graphical browsing.

2004-08-26: Additional information about the HapMap Project released
What is HapMap?,Origins of Haplotypes, Human Health Benefits, Populations Sampled, Ethical Issues, and Data Release Policy is now available.

2004-09-02 : Public data release #11
Genotypes, frequencies and assays for 693,255 SNPs (62,393,760 genotypes) released for bulk download and graphical browsing.

2004-09-28: Scheduled Network Outage
Due to schedule network maintenance at Cold Spring Harbor Laboratories, HapMap (and the related production sites) will be unavailable between 11PM (EDT) on Oct 2nd until approximately 6AM(EDT) on Oct 3rd. We apologize for the disruption. However, the Japanese mirror site will be available as usual.

2004-08-16 : Public data release #10
Genotypes, frequencies and assays for 661,094 SNPs (59,498,460 genotypes) released for bulk download and graphical browsing.

2004-07-20 : Public data release #9
Genotypes, frequencies and assays for 639,110 SNPs (57,519,900 genotypes) released for bulk download and graphical browsing.

2004-06-15 : Public data release #8
Genotypes, frequencies and assays for 614,030 SNPs (55,262,700 genotypes) released for bulk download and graphical browsing.

2004-05-27: 'Integrating ethics and science in the International HapMap Project'
Paper published in the Nature Reviews Genetics 2004 Jun;5(6):467-75 .

2004-05-26: HapMap Mirror Site now Available
The HapMap website is now mirrored in Japan at http://hapmap.jst.go.jp. Maintained by the Japan Science and Technology Agency's group, this mirror will provide faster services to users in Asia and Pacifica.

2004-05-04 : Public data release #7
Genotypes, frequencies and assays for 557,083 SNPs (50,137,470 genotypes) released for bulk download and graphical browsing.

2004-04-09 : Public data release #6
Genotypes, frequencies and assays for 462,670 SNPs (41,640,300 genotypes) released for bulk download and graphical browsing.

This meeting will discuss data analysis and methodological issues relevant to the International Haplotype Map Project. This will include approaches to describing linkage disequilibrium, properties of linkage disequilibrium, inference of haplotypes and haplotype frequencies, and methods for utilizing the haplotype map in association and other disease studies. The meeting will provide an important opportunity for a diverse community of investigators (both those involved directly in the project, and those in the broader community) to come together to define and debate a range of issues in the creation of the Haplotype Map resource.

The meeting is scheduled to begin with presentations and a reception from 6pm on April 18, and will conclude no later than 3pm on April 20. It is being hosted by the McKusick-Nathans Institute of Genetic Medicine/Johns Hopkins University and the National Human Genome Research Institute. For further details, to register, and/or to submit an abstract visit International HapMap Community Analysis Meeting website.

Investigators wishing to apply methods to the current data should use the March freeze of the HapMap data and of a denser data set, from the ENCODE project,available at www.hapmap.org/genotypes/ENCODE/.

2004-03-05 : Public data release #5
Genotypes, frequencies and assays for 369,784 SNPs (33,280,560 genotypes) released for bulk download and graphical browsing.

2004-02-06 : Public data release #4
Genotypes, frequencies and assays for 324,613 SNPs (29,215,170 genotypes) released for bulk download and graphical browsing.

2004-01-07 : Public data release #3
Genotypes, frequencies and assays for 274,571 SNPs (24 000,000 genotypes) released for bulk download and graphical browsing.